Laboratory diagnostic tests are not perfect and are not 100% accurate
- We do not have a test for every disease or virus but most of those pathogens that are of public health importance or have long term implications on your health can be tested
- No one single test can be used with absolute certainty to diagnose a disease. Often, we depend on a combination of tests to make a diagnosis
- Sometimes, we have to resort to trial treatment or empiric treatment if investigative tests are inconclusive. If the patient makes a therapeutic response and feels better, we have achieved our goal
- In PUO, we are looking for treatable causes and to rule out sinister causes eg. malignancies so that we do not miss opportunities for early treatment or intervention